Added: Arnisha Norrell - Date: 09.10.2021 07:26 - Views: 28926 - Clicks: 5019
Neglected diseases represent a major health problem. It is estimated that one third of the world population is infected with tuberculosis TB. Besides TB, Chagas disease, affects approximately 20 million people. Quinoxalines display great activities against TB and Chagas.
Forty new quinoxaline 1,4-di-N-oxide derivatives have been prepared and tested against M. Synthetic route to heterocycliccarboxylic acid 3-cyano-1,4-di- N -oxidequinoxalinyl -amide derivatives Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.
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Scheme 2 Synthetic route to heterocycliccarboxylic acid…. Scheme 2 Synthetic route to heterocycliccarboxylic acid 3-cyano-1,4-di- N -oxidequinoxalinyl -amide derivatives See this image and copyright information in PMC. Similar articles New 3-methylquinoxalinecarboxamide 1,4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents. Ancizu S, et al. Bioorg Med Chem.
Epub Feb PMID: Quinoxaline and quinoxaline-1,4-di-N-oxides: An emerging class of antimycobacterials. Keri RS, et al. Arch Pharm Weinheim. Epub Apr 3. PMID: Review. In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide. Villar R, et al. J Antimicrob Chemother. Epub May Synthesis and antituberculosis activity of new 2-quinoxalinecarbonitrile 1,4-di-N-oxides. Ortega MA, et al. Quinoxaline 1,4-di-N-oxide and the potential for treating tuberculosis.
Vicente E, et al. Infect Disord Drug Targets. See all similar articles. Miller EM, et al. Cerecetto H, et al.
Pharmaceuticals Basel. Cheng G, et al. Front Pharmacol. In silico studies of quinoxalinecarboxamide 1,4-di-n-oxide derivatives as antimycobacterial agents. Radwan AA, et al. See all "Cited by" articles. Synthesis of new quinoxalinecarboxylate 1,4-dioxide derivatives as anti-Mycobacterium tuberculosis agents. Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. Show all 30 references. Publication types Research Support, Non-U. Gov't Actions. MeSH terms Animals Actions.
Magnetic Resonance Spectroscopy Actions. Molecular Structure Actions. Rifampin Actions. Substances Antitubercular Agents Actions. Quinoxalines Actions. Copy Download.2 hits of acid
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